Blar i Bergen Open Research Archive på forfatter "Sjøgren, Thea"
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Immune regulatory mechanisms in endocrine autoimmune disorders
Sjøgren, Thea (Doctoral thesis, 2023-09-15)Ulike mekanismer eksisterer for at immunforsvaret skal lære å skille det som er eget fra det som er fremmed, også kjent som immunologisk toleranse. I noen tilfeller brytes denne toleransen, noe som kan føre til at enkelte ... -
Pharmacological treatment of the T-cell receptor signalling pathway in autoimmune Addison's disease - A pilotstudy with abatacept (CTLA4-Ig)
Sjøgren, Thea (Master thesis, 2020-06-12) -
Transcriptional Changes in Regulatory T Cells From Patients With Autoimmune Polyendocrine Syndrome Type 1 Suggest Functional Impairment of Lipid Metabolism and Gut Homing
Berger, Amund Holte; Bratland, Eirik; Sjøgren, Thea; Heimli, Marte; Tyssedal, Torgeir; Bruserud, Øyvind; Johansson, Stefan; Husebye, Eystein Sverre; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe (Journal article; Peer reviewed, 2021)Autoimmune polyendocrine syndrome type I (APS-1) is a monogenic model disorder of organ-specific autoimmunity caused by mutations in the Autoimmune regulator (AIRE) gene. AIRE facilitates the expression of organ-specific ... -
Vaccination prevents severe COVID-19 outcome in patients with neutralizing type 1 interferon autoantibodies
Wolff, Anette Susanne Bøe; Hansen, Lena; Grytaas, Marianne Aardal; Oftedal, Bergithe Eikeland; Breivik, Lars Ertesvåg; Zhou, Fan; Hufthammer, Karl Ove; Sjøgren, Thea; Olofsson, Jan Stefan; Trieu, Mai Chi; Meager, Anthony; Jørgensen, Anders Palmstrøm; Lima, Kari; Mohn, Kristin Greve-Isdahl; Langeland, Nina; Cox Brokstad, Rebecca Jane; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2023)A hallmark of patients with autoimmune polyendocrine syndrome type 1 (APS-1) is serological neutralizing autoantibodies against type 1 interferons (IFN-I). The presence of these antibodies has been associated with severe ...